Lawrence, who leads the Padres with a career-best 13 wins this season, is 0-2 in three starts against the Rockies this year despite pitching to a 3.44 ERA in those outings. The 28-year-old right-hander suffered a 5-2 home loss to Colorado on Sunday, giving up three runs and seven hits over seven innings.
Lawrence has lost two straight starts and five of seven decisions overall.
The Padres, who finished last in the NL West in each of the previous two seasons, are trying to return to the postseason for the first time since 1998.
They fell 2 1/2 games behind NL wild card leaders San Francisco and Houston after a 9-7 series-opening loss Thursday—San Diego’s seventh defeat in the last 10 games.
Mark Loretta, the team’s leading hitter, was back in the lineup Thursday after missing three games because of a bruised knuckle on his right ring finger. He went 1-for-5.
Colorado will give to ball to Shawn Estes, who tormented the Padres on the mound and at the plate in an 8-2 victory Saturday.
Estes allowed two runs and four hits over seven innings, matching the single-season team record for wins (14) by a left-hander, first set by Mike Hampton in 2001. He also singled, tripled and scored two runs.
In his previous three starts, Estes went 0-2 while allowing 18 runs and 27 hits in 15 2-3 innings.
“I just wanted to get back out there and turn things around,” he said. “It was a long five days. Now I can carry some momentum into my next start.”
Estes is 12-4 with a 3.52 ERA in 20 career starts against San Diego. The 12 wins are his most against any opponent.