In 10 career starts against the Devil Rays, the hard-throwing right-hander is 6-0 with a 2.49 ERA. In his lone start against Tampa Bay this season, Colon allowed two runs and two hits over seven innings in a 7-2 win on May 8.
Colon had his career-high six-game winning streak snapped on Thursday in a 6-1 loss to Baltimore. Colon allowed six runs, eight hits and walked a season-high six over 5 1-3 innings.
“I don’t have anything to blame it on. My location was bad and my mechanics were fine, I thought,” said Colon, who had a 2.54 ERA during his winning streak. “I just did not spot the ball where I wanted to.”
On Tuesday, Kelvim Escobar allowed five runs and six hits over 4 2-3 innings as the Angels dropped the series opener 8-3.
The Angels, who had won eight of 11 prior to the loss, now trail first-place Oakland by two games in the AL West.
Upton, the No. 2 overall pick in the 2002 draft, gave the Devil Rays a 2-1 lead in the third inning with an opposite-field shot to right. The homer came in the rookie shortstop’s 39th career at-bat.
“He’s got good power all over,” manager Lou Piniella said. “He’s looking more relaxed.”
Angels manager Mike Scioscia said he is impressed with the Devil Rays.
“They’ve got a lot of young talent,” Scioscia said. “They’re young and aggressive.”