Meche lost 5-2 to the Blue Jays on Friday, giving up four earned runs and seven hits over just four innings. He struck out one.
“It was almost like they were looking for certain pitches,” Meche said. “They were being really patient. The times I made good pitches, they kept fouling them off, pitch after pitch.”
The 24-year-old right-hander was coming off a 2-1 road victory over the AL East-leading New York Yankees, and had won his previous three starts with a 2.37 ERA while striking out 18.
Ryan Franklin, who suffered a 13-6 loss to Toronto last Wednesday, rebounded on Tuesday, pitching the Mariners to a 9-1 victory.
Seattle won for the seventh time in 10 games and remained four games ahead of second-place Oakland in the AL West. The Athletics beat Boston 3-2.
Edgar Martinez hit his 22nd homer for the Mariners and finished 4-for-5 with four RBIs.
The Blue Jays have lost three straight, falling three games below .500 for the first time since May 15.
Carlos Delgado drove in Toronto’s lone run. The All-Star first baseman was 3-for-4 and is hitting .452 (14-for-31) over his last eight games with three homers and 11 RBIs.
He leads the AL with 115 RBIs and his 33 homers rank third.
STANDINGS: Mariners - 1st place, AL West. Blue Jays - 3rd place, 16 1/2 GB, AL East.
MARINERS PROBABLE STARTER: Meche (13-8, 3.78 ERA). Meche is 1-1 all-time against the Blue Jays with a 6.30 ERA in two career starts.
BLUE JAYS PROBABLE STARTER: Josh Towers (2-1, 6.89 ERA). A reliever prior to the All-Star break, Towers earned an 8-5 victory at Oakland on Friday, giving up four earned runs and seven hits over five innings. It was his first win as a starter since Aug. 17, 2001, at Boston when he was with Baltimore. He lost his previous seven starts, including one this year. Towers lost his only previous start against Seattle on Sept. 9, 2001, giving up five earned runs and eight hits over six innings of a 6-0 road loss.
SEASON SERIES: Mariners, 3-2.
STREAKS AND NOTES: Mariners - 2B Boone has two homers and nine RBIs in his last nine games. … DH Martinez and 2B Boone are a combined 3-for-6 against RHP Towers with a homer and two RBIs apiece. … INF Cirillo entered Tuesday’s game in the fifth after 3B Willie Bloomquist left with a tight right quad. Blue Jays - 1B Delgado is 3-for-5 in his career against RHP Meche with a homer and an RBI. … CF Wells, who came in batting .375 (6-for-16) against Seattle this season, went 0-for-4 Tuesday. … Despite batting .176 (3-for-17) in his last five games, 3B Eric Hinske has two homers and four RBIs over the span.
ROAD/HOME RECORDS: Mariners - 37-22 on the road; Blue Jays - 26-33 at home.
INJURIES: Mariners - INF Greg Colbrunn (wrist), 15-day DL; INF Carlos Guillen (pelvis), 15-day DL; LHP Matt Thornton (elbow), 60-day DL. Blue Jays - RHP Cory Lidle (groin), 15-day DL; RHP Pete Walker (calf), 15-day DL; LHP Doug Creek (elbow), 60-day DL; RHP Bob File (calf), 60-day DL.