The 32-year-old right-hander has been the Mets’ best starter in recent weeks. He is 4-1 with a 1.50 ERA over his last five starts, not allowing more than three earned runs in any of those outings.
On Saturday, he held the Cincinnati Reds to no runs and four hits over six innings in a 6-2 win.
The Mets will look for another strong start from Trachsel as they try to snap a three-game losing streak.
New York comes in after being swept for the fourth time this season, losing 6-3 to the Atlanta Braves on Wednesday.
The Phillies, who trail the Arizona Diamondbacks by one game in the National League wild-card race, have won two straight following a season-high four-game losing streak.
First baseman Jim Thome got the day off to rest his ailing back, but he said his condition is not serious.
“It’s a little sore today,” Thome said. “I’ll be ready to go (Thursday).”
STANDINGS: Phillies - 2nd place, 8 1/2 GB, NL East. Mets - 5th place, 19 GB, NL East.
PHILLIES PROBABLE STARTER: Vicente Padilla (7-8, 3.93 ERA). After allowing no more than two earned runs in four consecutive starts, Padilla struggled in his last outing. He allowed five runs and six hits over five innings Saturday in a 5-4 loss to the Florida Marlins. In 14 career games against the Mets, the 25-year-old right-hander is 5-1 with a 3.08 ERA.
METS PROBABLE STARTER: Trachsel (8-5, 4.10 ERA). In 18 career games against the Phillies, Trachsel is 7-5 with a 3.24 ERA.
OFFENSIVE LEADERS: Phillies - Mike Lieberthal, .326 avg.; Thome, 22 HRs, 63 RBIs and 58 runs; Abreu, Placido Polanco and Jimmy Rollins, 9 SBs. Mets - Cliff Floyd, .272 avg. and 47 RBIs; Jeromy Burnitz, 18 HRs; Ty Wigginton, 50 runs; Roger Cedeno, 7 SBs.
SEASON SERIES: Mets, 4-2.
STREAKS AND NOTES: Phillies - SS Rollins is batting .185 (5-for-27) in his career against RHP Trachsel. … RF Abreu has hit safely in seven straight games, batting .269 (7-for-26) during that span. … LF Pat Burrell, batting .192, is 1-for-15 in his last four games. Mets - OF Cedeno is batting .385 (5-for-13) in his career against RHP Padilla. … LHP Mike Stanton, on the disabled list since May 3 because of an inflamed left knee, plans to make his second minor league rehabilitation appearance on Thursday. … OF Burnitz has nine RBIs during a seven-game RBI streak.
ROAD/HOME RECORDS: Phillies - 23-19 on the road; Mets - 19-25 at home.
INJURIES: Phillies - INF Tyler Houston (finger), 15-day DL; RHP David Coggin (shoulder), 15-day DL. Mets - C Mike Piazza (groin), 15-day DL; LHP Al Leiter (knee), 15-day DL; LHP Stanton (knee), 15-day DL; RHP Pedro Astacio (shoulder), 60-day DL; RHP Grant Roberts (shoulder), 60-day DL; RHP Scott Strickland (groin), 60-day DL; 1B Mo Vaughn (knee), 60-day DL.