The 24-year-old right-hander was recalled from Triple-A Albuquerque to fill the rotation spot of left-hander Mark Redman, who is expected to be sidelined two-to-four weeks with a broken thumb on his pitching hand.
Wayne made an emergency start in place of injured right-hander A.J. Burnett on Monday, but lost 7-1 at Arizona. He gave up four earned runs and seven hits over 5 1-3 innings in his first start of the season and sixth of his career.
The Marlins, who have seven come-from-behind victories this season, blew a 3-0 fifth-inning lead in losing the opener on Friday 4-3.
Luis Castillo went 1-for-3 to stretch his hitting streak to 14 games, the longest active streak in the NL and the longest for the Marlins this season. The second baseman is batting .365 (23-for-63) during his run with a double, a triple, a homer and four RBIs.
The Astros needed six pitchers Friday to pull out their second win in nine games.
Scott Linebrink allowed three runs and six hits in five innings and Ricky Stone, Bruce Chen, Brandon Puffer, Brad Lidge and Billy Wagner shut down the Marlins over the last four, with Wagner pitching a perfect ninth for his fifth save in six chances.
Adam Everett, brought back from the minor leagues earlier in the day, went 2-for-3 with an RBI for the Astros. Everett, Houston’s opening-day shortstop in 2002 before being demoted, also got the first triple of his major league career. He started at shortstop in place of Julio Lugo, who was dropped from the roster Thursday after he was arrested on a charge of assaulting his wife.
“We had a good game all the way around,” Houston manager Jimy Williams said. “We used six pitchers. Sometimes you can win with one, and sometimes it takes six. We’ve had a lot of individuals come out of the bullpen and pitch some good games.”
STANDINGS: Marlins - 4th place, 4 1/2 GB, NL East. Astros - 4th place (tied), 4 1/2 GB, NL Central.
MARLINS PROBABLE STARTER: Wayne (0-1, 6.75 ERA). Wayne, acquired from Montreal in the Cliff Floyd trade last season, has never faced the Astros.
ASTROS PROBABLE STARTER: Tim Redding (2-2, 3.29 ERA). The right-hander hasn’t given up more than three earned runs in any of his five starts this season, but the Astros are just 3-2. He won his second straight start Sunday, a 6-3 decision at Montreal. He gave up three earned runs and six hits while striking out a season-high seven over six innings. Redding is facing the Marlins for the first time.
OFFENSIVE LEADERS: Marlins - Gonzalez, .333 avg.; Mike Lowell, 8 HRs and 19 runs; Lowell and Gonzalez, 23 RBIs; Juan Pierre, 12 SBs. Astros - Jeff Bagwell, .316 avg., 10 HRs and 19 RBIs; Craig Biggio, 18 runs; Richard Hidalgo, 3 SBs.
SEASON SERIES: Astros, 1-0.
STREAKS AND NOTES: Marlins - Florida leads the majors with 49 stolen bases. … The Marlins have a major league-high 15 triples. … C Ivan Rodriguez is the only current Marlin that has faced Redding. He is 1-for-1. Astros - LHP Wagner made his 400th career appearance on Friday. … CF Biggio went 1-for-3 Friday with an RBI, his second in his last six games. He is batting .143 (3-for-21) over that span. … Houston relievers had a 3.12 ERA coming into Friday’s game, third in the NL.
ROAD/HOME RECORDS: Marlins - 6-10 on the road; Astros - 6-7 at home.
INJURIES: Marlins - OF Abraham Nunez (hamstring), 15-day DL; RHP Burnett (elbow), 15-day DL; LHP Redman (thumb), day-to-day. Astros - LHP Carlos Hernandez (rotator cuff), 15-day DL; RHP Brian Moehler (right flexor tendon), 15-day DL.