Spiller (home) vs Seattle or
Ridle (home) vs 49'rs
A toss up for me, either one
Ouch, good RB's, awful matchups. I'd go with Spiller, because the Pats can do other things offensively to win, whereas the Bills basically have to ride him.
WR: Alexander (v.Car), LMoore (v.TB), Hilton (@Hou), Austin (v.Pit), or Boldin (v.Den)? (Pick a #1 and #2, since I'm starting Garcon over #2 if RG3 plays)
TE: Myers (v.KC) or Bennett (@Atl)?