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Jake Locker, Santonio Holmes headline Week 4 injuries

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Jake Locker's rough go against the Bucs wasn't held against him. (Getty Images)

Tennessee Titans quarterback Jake Locker re-injured his left (non-throwing) shoulder when he was hit by blitzing Houston Texans safety Glover Quin in the first quarter of the Texans' 38-14 win on Sunday. Locker suffered a dislocated shoulder in the 2012 regular- season opener against the New England Patriots and has been playing with a harness ever since. The 2011 first-round pick out of the University of Washington will undergo an MRI on Monday, at which point his status for next Sunday's game against Jared Allen and the Minnesota Vikings will be determined.

Philadelphia Eagles cornerback Nnamdi Asomugha injured his eye while attempting to press New York Giants wide receiver Ramses Barden at the line of scrimmage with around 12 minutes to play in the second quarter on Sunday night. Barden appeared to inadvertently poked Asomugha in the right eye and reports from the sideline were that he was sent to Wills Eye Hospital, but that turned out to be a false alarm as the cornerback returned to the field in the second half and was flagged for and drew pass interference penalties on the final drive of the Eagles' 19-17 win over the Giants.

The Giants lost safety Kenny Phillips to a right knee injury in the first quarter. According to Jenny Vrentas of The Star-Ledger, head coach Tom Coughlin wasn't sure how much time Phillips would miss.

As if the New York Jets do not have enough problems, wide receiver Santonio Holmes left Sunday's 34-0 loss to the San Francisco 49ers with a foot injury. Holmes was injured while making a 4-yard reception on the opening play of the fourth quarter. The injury was of the non-contact variety and to add insult to injury, Holmes let go of the football, which was scooped by 49ers cornerback Carlos Rogers and returned 51 yards for a touchdown.

Holmes was carted to the locker room and will undergo an MRI on Monday. While the playing status of the veteran receiver will not be known until Monday, Holmes' financial future is secure. Holmes is earning $7.75 million in fully guaranteed base salary this season and, because he was on the Jets' roster on Feb. 12, 2012, $7.75 million of his $11 million base salary next season is fully guaranteed.

Wide receiver Greg Jennings re-injured his groin during the first half of the Green Bay Packers' 28-27 win over the New Orleans Saints. Jennings had a 9-yard touchdown on his only reception on Sunday, giving him 12 receptions for 78 yards and one touchdown in his pivotal contract season of 2012. Jennings also has per-game roster bonuses ($25,000 per game), so any time missed this season will have financial ramifications now and moving forward.

Washington Redskins safety Brandon Meriweather and wide receiver Aldrick Robinson were injured during a collision during pregame warm-ups before their 24-22 win over the Tampa Bay Buccaneers. Robinson was hit in the head by Meriweather, who landed awkwardly on a left knee that has kept him out of the first three games of the season. Buccaneers cornerback Eric Wright took a knee to the head in the third quarter and left the game.

For the second consecutive weeks, Jacksonville Jaguars wide receiver Laurent Robinson left after taking a blow to the head. Signed to a five-year, $32.5 million contract on March 15, Robinson has nine receptions for 134 yards on the season and the club will likely be very cautious about rushing him back to the field. The Jaguars host the Chicago Bears next Sunday and then have a bye week.

The Denver Broncos lost starting center J.D. Walton for the season to a broken ankle during Sunday's 37-6 blowout of the Oakland Raiders. A third-round pick out of Baylor by the Broncos in 2010, Walton has started 36 straight games and, according to official playing-time documents, had missed just one snap in his career up until suffering his injury on Sunday. Walton will be replaced in the starting lineup by veteran Dan Koppen, who was signed to the 53-man roster on Sept. 11.

First-round linebacker Dont'a Hightower injured his hamstring in the first quarter of the New England Patriots' 52-28 win over the Buffalo Bills. The Boston Herald reports that Hightower's hamstring is "good."

Five Bills starters left the game with injuries, including starting left tackle Cordy Glenn and right guard Kraig Urbik who could miss significant time with ankle injuries. Safety Jairus Byrd left the game with a hip injury and tight end Scott Chandler and wide receiver Donald Jones exited with head injuries, though Jay Skurski of The Buffalo News reports both passed concussion tests after the game and should be fine. Chandler and Jones have combined for six of the Bills' 12 passing touchdowns this season.

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