First, you need to go here and observe the projected standings given how everyone's played so far. It's not a perfect prediction, since there's always the chance of a hot or cold streak, but it'll give you a good idea of who needs to do what in order to stay in the game.
It's too early to project winners and losers, but we can start with a few names:
Arjun Atwal: The defending champ at the Wyndham followed up this year with a cut, and thus sits right on the line. It'll be a nervous few days for him.
Paul Casey: Ranked 147th coming in, his strong play has put him right on the bubble as well. He'll need to sustain, but it's out there.
Justin Leonard: See Casey. He was 142nd coming into the weekend, but a solid early performance at the Wyndham has him on the cusp of the playoff cut line.
Padraig Harrington: The freefall continues, and above, Paddy is watching it fall. He was 130 coming in, so he needed a solid-but-not-outstanding performance. He's put in a not-solid performance so far, though he did make the cut and still has flickering hopes.
Daniel Summerhays: Could be the story of the tournament. Ranked 178th coming in, he reached T2 and briefly got inside the playoff cut line. Probably needs a victory and/or a major meltdown from other players to make the jump.
Camilo Villegas: Sitting on the 125-rank cutline coming in, a strong first couple days have given him a bit of breathing room.
Matt Jones, David Mathis, Cameron Beckman: All three of these gentlemen were inside the cut line coming in, all three missed the Wyndham cut, and now are almost certainly out of the playoffs.
Billy Mayfair, James Driscoll, Steve Flesch, Steven Bowditch: Missed cuts hurt their chances, but they could be far enough inside the playoff cut line to hang on for another week.
Plenty of golf remains, but the will-they-or-won't-they drama continues at the bottom of the standings. And there are half a dozen guys now at home wondering what-if.